neob {sesame}R Documentation

Negative control plus out-of-band background correction

Description

The function takes a SigDF and returns a modified SigDF with background subtracted. Background was modelled in a normal distribution and true signal in an exponential distribution. The Norm-Exp deconvolution is parameterized using both negative control and Out-Of-Band (oob) probes

Usage

neob(sdf, offset = 15)

Arguments

sdf

a SigDF

offset

offset

Value

a new SigDF with neob background correction

Examples

sdf <- sesameDataGet('EPIC.1.SigDF')
sdf.nb <- neob(sdf)

[Package sesame version 1.12.6 Index]