SPsimSeq-package {SPsimSeq}R Documentation

SPsimSeq package

Description

SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently, simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.

Author(s)

Alemu Takele Assefa alemutak@hotmail.com

Stijn Hawinkel stijnhawinkel@hotmail.com

References


[Package SPsimSeq version 1.3.0 Index]