GetTD {SCnorm} | R Documentation |
This is an internal fitting of the group regression. For a single combination of possible tau and d values the group regression is fist fit, then predicted values are obtained and regressed against the original sequencing depths. The estimates slope is passed back to the SCnorm_fit() function.
GetTD(x, InputData)
x |
specifies a column of the grid matrix of tau and d. |
InputData |
contains the expression values, sequencing depths to fit the group regression, and the quantile used in the individual gene regression for grouping. |
estimated count-depth relationship of predicted values for one value of tau and degree.
Rhonda Bacher