rnb.execute.lump {RnBeads}R Documentation

Leukocytes unmethylation for purity

Description

Implementation of the LUMP (Leukocytes UnMethylation for Purity) algorithm for purity estimation on methylation datasets.

Usage

rnb.execute.lump(dataset)

Arguments

dataset

Methylation dataset to study, provided as an object of type inheriting RnBSet.

Details

The LUMP algorithm is developed by Dvir Aran, Marina Sirota and Atul J. Buttea.

Value

Purity esimates provided as a vector of values in the range [0, 1]. The attribute "sites" contains the number of sites used in estimating the immune cell proportions. In case the dataset does not contain measurements for any of the sites on which LUMP focuses, the return values is NULL.

Author(s)

Yassen Assenov


[Package RnBeads version 2.12.0 Index]