computeAmax {PharmacoGx} | R Documentation |
Fits dose-response curves to data given by the user
and returns the Amax of the fitted curve.
Amax: 100 - viability at maximum concentarion (in fitted curve)
Description
Fits dose-response curves to data given by the user
and returns the Amax of the fitted curve.
Amax: 100 - viability at maximum concentarion (in fitted curve)
Usage
computeAmax(concentration, viability, trunc = TRUE, verbose = FALSE)
Arguments
concentration |
numeric is a vector of drug concentrations.
|
viability |
numeric is a vector whose entries are the viability values observed in the presence of the
drug concentrations whose logarithms are in the corresponding entries of the log_conc, expressed as percentages
of viability in the absence of any drug.
|
trunc |
logical , if true, causes viability data to be truncated to lie between 0 and 1 before
curve-fitting is performed.
|
verbose |
logical should warnings be printed
|
Value
The numerical Amax
Examples
dose <- c("0.0025","0.008","0.025","0.08","0.25","0.8","2.53","8")
viability <- c("108.67","111","102.16","100.27","90","87","74","57")
computeAmax(dose, viability)
[Package
PharmacoGx version 2.5.3
Index]