motifRankingForSequence,MotifEnrichmentResults-method {PWMEnrich}R Documentation

Get a ranking of motifs by their enrichment in one specific sequence

Description

Get a ranking of motifs by their enrichment in one specific sequence

Usage

## S4 method for signature 'MotifEnrichmentResults'
motifRankingForSequence(
  obj,
  seq.id,
  bg = TRUE,
  id = FALSE,
  order = FALSE,
  rank = FALSE,
  unique = FALSE,
  ...
)

Arguments

obj

a MotifEnrichmentResults object

seq.id

either the sequence number or sequence name

bg

if to use background corrected P-values to do the ranking (if available)

id

if to show PWM IDs instead of target TF names

order

if to output the ordering of PWMs instead of actual P-values or raw values

rank

if the output should be rank of a PWM instead of actual P-values or raw values

unique

if TRUE, only the best rank is taken for each TF (only when id = FALSE, order = FALSE)

...

currently unused

Value

a vector of P-values or raw enrichments sorted such that the first motif is most enriched

Examples

if(requireNamespace("PWMEnrich.Dmelanogaster.background")){
   ###
   # load the pre-compiled lognormal background
   data(PWMLogn.dm3.MotifDb.Dmel, package = "PWMEnrich.Dmelanogaster.background")

   # scan two sequences for motif enrichment
   sequences = list(DNAString("GAAGTATCAAGTGACCAGTAAGTCCCAGATGA"), 
     DNAString("AGGTAGATAGAACAGTAGGCAATGAAGCCGATG"))
   res = motifEnrichment(sequences, PWMLogn.dm3.MotifDb.Dmel)

   # most enriched in the second sequences (sorted by lognormal background P-value)
   head(motifRankingForSequence(res, 2))

   # return unique TFs enriched in sequence 2
   head(motifRankingForSequence(res, 2, unique=TRUE))

   # sorted by raw affinity instead of P-value
   head(motifRankingForSequence(res, 2, bg=FALSE))

   # show IDs instead of target TF names
   head(motifRankingForSequence(res, 2, id=TRUE))

   # output the rank instead of P-value
   head(motifRankingForSequence(res, 2, rank=TRUE))
}

[Package PWMEnrich version 4.29.1 Index]