getGlobalAlignment {DIAlignR} | R Documentation |
This function selects features from oswFiles which has m-score < maxFdrLoess. It fits linear/loess regression on these feature. Retention-time mapping is established from reference to experiment run.
getGlobalAlignment( oswFiles, ref, eXp, fitType = "linear", maxFdrGlobal = 0.01, spanvalue = 0.1 )
oswFiles |
(list of data-frames) it is output from getFeatures function. |
ref |
(string) Must be a combination of "run" and an iteger e.g. "run2". |
eXp |
(string) Must be a combination of "run" and an iteger e.g. "run2". |
fitType |
(string) Must be from "loess" or "linear". |
maxFdrGlobal |
(numeric) A numeric value between 0 and 1. Features should have m-score lower than this value for participation in global fit. |
spanvalue |
(numeric) Spanvalue for LOESS fit. For targeted proteomics 0.1 could be used. |
An object of class "loess".
Shubham Gupta, shubh.gupta@mail.utoronto.ca
ORCID: 0000-0003-3500-8152
License: (c) Author (2019) + GPL-3 Date: 2019-12-14
data(oswFiles_DIAlignR, package="DIAlignR") fit <- getGlobalAlignment(oswFiles = oswFiles_DIAlignR, ref = "run1", eXp = "run2", fitType = "linear", maxFdrGlobal = 0.05, spanvalue = 0.1)