calcWeights |
Obtain weights as posterior probabilities to calculate the consensus null |
estNormal |
Fast estimation of mean and standard deviation of a normal distrbution, optionally with weights |
estP0 |
Estimate the fraction of true null hypotheses. |
getApproxCovar |
Obtain a null covariance matrix of binned test statistics |
getFdr |
Calculate tail-area (Fdr) and local (fdr) false discovery rates, based on a certain null distribution |
getG0 |
Obtain the consensus null |
getTestStats |
A function to calculate observed and permuation z-statistics on a n-by-p matrix of observations |
getTstat |
A function to obtain a t-test statistic efficiently. For internal use only |
plotApproxCovar |
Plot an approximatio of the correlation structure of the test statistics |
plotNull |
Plot the obtained null distribution along with a histogram of observed test statistics |
ptEdit |
A custom function to calculate the distribution function of the t-test statistic. For internal use only |
qtEdit |
A custom function to calculate the quantile function of the t-test statistic. For internal use only |
quantCorrect |
Correct quantiles by not returning 0 or 1 |
reconsi |
Perform simultaneous inference through collapsed resampling null distributions |
rowMultiply |
A function to efficiently row multiply a a-by-b matrix by a vector of length b. More memory intensive but that does not matter with given matrix sizes |
stabExp |
A function to numerically stabilize an exponentiation. For internal use only |
testDAA |
A function to test for differential absolute abundance on a phyloseq object |
testDAA-method |
A function to test for differential absolute abundance on a phyloseq object |
Vandeputte |
Microbiomes of Crohn's disease patients and healthy controls |