Deconvolution of mixed cells from spatial and/or bulk gene expression data


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Documentation for package ‘SpatialDecon’ version 1.4.3

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SpatialDecon-package SpatialDecon: A package for computating the notorious bar statistic.
cellcols Default colors for the cell types in the safeTME matrix
collapseCellTypes Collapse related cell types within a deconvolution result
create_profile_matrix Create Custom Cell Profile Matrix
derive_GeoMx_background Derive background at the scale of the normalized data for GeoMx data
download_profile_matrix Download a cell profile matrix
florets Draw coxcomb plots as points in a graphics window
mean.resid.sd Genes' biological variability in immune deconvolution from TCGA.
mergeTumorIntoX Estimate a tumor-specific profile and merge it with the pre-specified cell profile matrix (X)
mini_geomx_dataset Small example GeoMx data
mini_singleCell_dataset Mini human colon single cell dataset
nsclc Large example GeoMx data
reverseDecon Reverse deconvolution
runCollapseCellTypes Run collapseCellTypes
runCollapseCellTypes-method Collapse related cell types within a deconvolution result
runErrorModel Apply error model to estimate technical SD from raw counts
runMergeTumorIntoX Run MergeTumorIntoX
runMergeTumorIntoX-method Run mergeTumorIntoX on a NanostringGeomxSet object
runReverseDecon Run Reversedecon
runReverseDecon-method Run reversedecon on a NanostringGeomxSet object
runspatialdecon Run spatialdecon
runspatialdecon-method Run spatialdecon on a NanostringGeomxSet object
runspatialdecon-method Run spatialdecon on a Seurat object
safeTME SafeTME matrix
safeTME.matches Mapping from granularly-defined cell populations to broaded cell populations
spatialdecon Mixed cell deconvolution of spatiall-resolved gene expression data
TIL_barplot Barplot of abundance estimates