Changes in version 1.1.0 o Normalization factors in differential loop calling are inferred from the loops object if present. o Added functions to annotate loops with differential expression and subset only differential enhancer-promoter loops. o Added function to annotate anchors with numeric scores from .bigwig and .bed files. o Functions that support integration of transcription data. o Support for reading in files processed by mango now available in the loopsMake.mango function. o Implemented mango bias corrected statistics in mangoCorrection function. o Significant rewrite of the vignette. o Consolidation of loopFit object to loops object. Changes in version 1.0.0 o Initial release to Bioconductor. o Added NEWS file. o Fixes to documentation. o Improved automated ploting including different colors. o Enhanced loop annotation.