DOI: 10.18129/B9.bioc.DESeq    

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This package is for version 3.12 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see DESeq (See replacement DESeq2).

Differential gene expression analysis based on the negative binomial distribution

Bioconductor version: 3.12

Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution

Author: Simon Anders, EMBL Heidelberg <sanders at>

Maintainer: Simon Anders <sanders at>

Citation (from within R, enter citation("DESeq")):


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biocViews ChIPSeq, DifferentialExpression, ImmunoOncology, RNASeq, SAGE, Sequencing, Software
Version 1.42.0
In Bioconductor since BioC 2.6 (R-2.11) (11 years)
License GPL (>= 3)
Depends BiocGenerics(>= 0.7.5), Biobase(>= 2.21.7), locfit, lattice
Imports genefilter, geneplotter, methods, MASS, RColorBrewer
Suggests pasilla(>= 0.2.10), vsn, gplots
Depends On Me DBChIP, EDDA, metaseqR, Polyfit, SeqGSEA, tRanslatome
Imports Me APAlyzer, ArrayExpressHTS, DEsubs, easyRNASeq, EDDA, rnaSeqMap, scGPS, vulcan
Suggests Me BitSeq, dexus, ELBOW, IHWpaper, PROPER, SSPA, ToPASeq, XBSeq
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