[ overview ]
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Introduction
exploRase is a MetNet tool written in
R
for the exploratory multivariate analysis of Systems Biology data.
It provides a graphical user interface (GUI) on top
of the analysis functionality provided by R and the
Bioconductor project.
exploRase is designed to be accessible to biologists analyzing omics data
in the context of metabolic and regulatory networks.
Features
- Provides a biologist-accessible GUI to R analysis functionality, such as
distance measures, clustering, pattern-finding, and modeling.
- Integrates the analysis with interactive graphics, using GGobi.
- Handles transcriptomic, metabolomic, and proteomic data.
- Simplifies the loading of experimental data into R and GGobi.
- Supports the storage of lists of "interesting" entities for future sessions.
- Links sortable tables of entity metadata to GGobi plots by color coding.
- Provides automatic access to AtGeneSearch, the web interface to
MetNetDB.
- Saves calculated statistics.
Components
- GTK+: The premier open-source graphical user interface toolkit.
- R: A sweet open-source platform for statistical computing.
- GGobi: The definitive open-source interactive graphics platform.
- rggobi: Let's R talk to ggobi.
- RGtk2: Let's R talk to GTK+.
Acknowledgements:
This work in funded by NSF Arabidopsis 2010 grants DB10209809 and DB10520267.
The people involved in the development are Eun-Kyung Lee, Di Cook,
Michael Lawrence, Heike Hofmann, Hai-Qing You, Eve Wurtele,
Dongshin Kim, Jihong Kim, Hogeun An.
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