DOI: 10.18129/B9.bioc.synergyfinder    

This package is for version 3.10 of Bioconductor; for the stable, up-to-date release version, see synergyfinder.

Calculate and Visualize Synergy Scores for Drug Combinations

Bioconductor version: 3.10

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Author: Liye He <liye.he at>, Jing Tang <jing.tang at>, Shuyu Zheng <shuyu.zheng at>

Maintainer: Shuyu Zheng <shuyu.zheng at>

Citation (from within R, enter citation("synergyfinder")):


To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



PDF R Script synergyfinder
PDF   Reference Manual
Text   NEWS


biocViews Software, StatisticalMethod
Version 2.0.12
In Bioconductor since BioC 3.4 (R-3.3) (3.5 years)
License Mozilla Public License 2.0
Depends R (>= 3.6.0), methods
Imports drc (>= 2.5-12), reshape2 (>= 1.4.1), ggplot2 (>= 2.1.0), grid (>= 3.2.4), lattice (>= 0.20-33), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
Suggests knitr, rmarkdown
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package synergyfinder_2.0.12.tar.gz
Windows Binary
Mac OS X 10.11 (El Capitan) synergyfinder_2.0.12.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
Package Short Url
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: