DOI: 10.18129/B9.bioc.LowMACA    

This package is for version 3.10 of Bioconductor; for the stable, up-to-date release version, see LowMACA.

LowMACA - Low frequency Mutation Analysis via Consensus Alignment

Bioconductor version: 3.10

The LowMACA package is a simple suite of tools to investigate and analyze the mutation profile of several proteins or pfam domains via consensus alignment. You can conduct an hypothesis driven exploratory analysis using our package simply providing a set of genes or pfam domains of your interest.

Author: Stefano de Pretis , Giorgio Melloni

Maintainer: Stefano de Pretis <ste.depo at gmail.com>, Giorgio Melloni <melloni.giorgio at gmail.com>

Citation (from within R, enter citation("LowMACA")):


To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



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biocViews Alignment, DataImport, MultipleSequenceAlignment, SequenceMatching, Sequencing, Software, SomaticMutation, WholeGenome
Version 1.16.0
In Bioconductor since BioC 3.1 (R-3.2) (5 years)
License GPL-3
Depends R (>= 2.10)
Imports cgdsr, parallel, stringr, reshape2, data.table, RColorBrewer, methods, LowMACAAnnotation, BiocParallel, motifStack, Biostrings, httr, grid, gridBase
Suggests BiocStyle, knitr, rmarkdown
SystemRequirements clustalo, gs, perl
Depends On Me
Imports Me
Suggests Me
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Follow Installation instructions to use this package in your R session.

Source Package LowMACA_1.16.0.tar.gz
Windows Binary LowMACA_1.16.0.zip
Mac OS X 10.11 (El Capitan) LowMACA_1.16.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/LowMACA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/LowMACA
Package Short Url https://bioconductor.org/packages/LowMACA/
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