Inference of differential exon usage in RNA-Seq

Bioconductor version: 2.9

The package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.

Author: Simon Anders <sanders at> and Alejandro Reyes <areyes at>, both at EMBL Heidelberg

Maintainer: Alejandro Reyes <reyes at>

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PDF R Script Analyzing RNA-seq data for differential exon usage with the "DEXSeq" package
PDF   Reference Manual
Text   NEWS


biocViews HighThroughputSequencing, RNAseq, DifferentialExpression
Depends Biobase(>= 2.13.11)
Imports hwriter, methods, stringr, statmod (>= 1.4.12)
Suggests pasilla(>= 0.2.6)
System Requirements
License GPL (>= 3)
Depends On Me pasilla
Imports Me
Suggests Me GenomicRanges
Version 1.0.2
Since Bioconductor 2.9 (R-2.14)

Package Downloads

Package Source DEXSeq_1.0.2.tar.gz
Windows Binary (32- & 64-bit)
MacOS 10.5 (Leopard) binary DEXSeq_1.0.2.tgz
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Fred Hutchinson Cancer Research Center