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Significance Analysis of Function and Expression

Bioconductor version: 2.14

SAFE is a resampling-based method for testing functional categories in gene expression experiments. SAFE can be applied to 2-sample and multi-class comparisons, or simple linear regressions. Other experimental designs can also be accommodated through user-defined functions.

Author: William T. Barry

Maintainer: William T. Barry <bbarry at>

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PDF R Script SAFE manual
PDF   Reference Manual


biocViews FunctionalAnnotation, GeneExpression, Software
Version 3.4.0
In Bioconductor since BioC 1.6 (R-2.1) or earlier
License GPL (>= 2)
Depends R (>= 2.4.0), AnnotationDbi, Biobase, methods, SparseM
Suggests GO.db, KEGG.db, PFAM.db, reactome.db, hgu133a.db, breastCancerUPP, survival, foreach, doRNG, Rgraphviz, GOstats
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Package Source safe_3.4.0.tar.gz
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