Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

Bioconductor version: Release (2.12)

This package contains the experimental data and a complete executable transcript (vignette) of the analysis of the HCT116 genetic interaction matrix presented in the paper "Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping" by C. Laufer, B. Fischer, M. Billmann, W. Huber, M. Boutros; Nature Methods (2013) 10:427-31. doi: 10.1038/nmeth.2436.

Author: Bernd Fischer

Maintainer: Bernd Fischer <bernd.fischer at embl.de>

To install this package, start R and enter:


To cite this package in a publication, start R and enter:



PDF R Script HD2013SGI
PDF   Reference Manual


biocViews Cancer, CellBasedAssays, CellBiology, Colon, ExperimentData, NetworkAnalysis, QualityControl
Version 1.00.1
License Artistic-2.0
Depends RColorBrewer, gplots, geneplotter, splots, limma, vcd, LSD, EBImage
System Requirements GNU make
Depends On Me
Imports Me
Suggests Me

Package Downloads

Package Source HD2013SGI_1.00.1.tar.gz
Windows Binary HD2013SGI_1.00.1.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) HD2013SGI_1.00.1.tgz
Package Downloads Report Download Stats

Mailing Lists »

Post questions about Bioconductor packages to our mailing lists. Read the posting guide before posting!

Fred Hutchinson Cancer Research Center