Bioconductor version: 2.10
This package provides tools for the analysis of high-throughput assays that were performed in 384-well microtitre plate (or analogous) formats. The functionality includes data import and management, normalisation, quality assessment, replicate summarisation and statistical scoring. A webpage that provides a detailed graphical overview over the data and analysis results is produced. In our work, we have applied the package to RNAi screens on fly and human cells, and for screens of yeast libraries. See ?cellHTS2 for a brief introduction.
Author: Ligia Bras, Wolfgang Huber <whuber at embl.de>, Michael Boutros <m.boutros at dkfz.de>, Gregoire Pau <gpau at embl.de>, Florian Hahne <florian.hahne at novartis.com>
Maintainer: Joseph Barry <joseph.barry at embl.de>
To install this package, start R and enter:
source("http://bioconductor.org/biocLite.R") biocLite("cellHTS2")
To cite this package in a publication, start R and enter:
citation("cellHTS2")
R Script | Main vignette (complete version): End-to-end analysis of cell-based screens | |
R Script | Main vignette: End-to-end analysis of cell-based screens | |
R Script | Supplement: enhancer-suppressor screens | |
R Script | Supplement: multi-channel assays | |
Reference Manual |
biocViews | CellBasedAssays, Preprocessing, Software, Visualization |
Depends | R (>= 2.10), RColorBrewer, Biobase, methods, genefilter, splots, vsn, hwriter, locfit, grid |
Imports | prada, GSEABase, Category, stats4 |
Suggests | |
System Requirements | |
License | Artistic-2.0 |
URL | http://www.dkfz.de/signaling, http://www.ebi.ac.uk/huber |
Depends On Me | coRNAi, HTSanalyzeR, imageHTS |
Imports Me | HTSanalyzeR, RNAinteract |
Suggests Me | |
Version | 2.20.0 |
Since | Bioconductor 2.1 (R-2.6) |
Package Source | cellHTS2_2.20.0.tar.gz |
Windows Binary | cellHTS2_2.20.0.zip (32- & 64-bit) |
MacOS 10.5 (Leopard) binary | cellHTS2_2.20.0.tgz |
Package Downloads Report | Download Stats |
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