Package: affxparser =================== Version: 1.45.1 [2016-09-16] o CLEANUP: Dropped obsolete src/R_affx_test.*cmdline.cpp files. o CLEANUP: Using c(x,y) instead of append(x,y) internally. Version: 1.45.0 [2015-05-03] o The version number was bumped for the Bioconductor devel version, which is now BioC v3.4 for R (>= 3.3.0). Version: 1.44.0 [2015-05-03] o The version number was bumped for the Bioconductor release version, which is now BioC v3.3 for R (>= 3.3.0). Version: 1.43.2 [2016-04-05] o Version bump for Bioconductor. Version: 1.43.1-9000 [2016-04-05] o WINDOWS: Package now compiles with both the old gcc-4.6.3 toolchain as well as the new gcc-4.9.3 toolchain - introduced in R (>= 3.3.0). Thanks to Jim Hester and Dan Tenenbaum for help with this. Version: 1.43.1 [2016-02-28] o Fixed a bug related to including and extern C, reported by Brian Ripley. o The DLL is now unloaded when the package is unloaded. Version: 1.43.0 [2015-10-23] o The version number was bumped for the Bioconductor devel version, which is now BioC v3.3 for R (>= 3.3.0). Version: 1.42.0 [2015-10-13] o The version number was bumped for the Bioconductor release version, which is now BioC v3.2 for R (>= 3.2.2). Version: 1.41.7 [2015-09-14] o ROBUSTNESS: Explicitly importing core R functions. Version: 1.41.6 [2015-07-29] o Updated the BiocViews field of DESCRIPTION. Version: 1.41.5 [2015-06-17] o New maintainer address (in all fields). Version: 1.41.4 [2015-05-26] o New maintainer address. Version: 1.41.3 [2015-05-13] o AVAILABILITY: Removed requirement for 'GNU make'. Version: 1.41.2 [2015-05-05] o BUG FIX/ROBUSTNESS: readCelHeader() and readCel() would core dump R/affxparser if trying to read multi-channel CEL files (Issue #16). Now an error is generated instead. Multi-channel CEL files (e.g. Axiom) are not supported by affxparser. Thanks to Kevin McLoughlin (Lawrence Livermore National Laboratory, USA) for reporting on this. o BUG FIX/ROBUSTNESS: readCelHeader() and readCel() on corrupt CEL files could core dump R/affparser (Issues #13 & #15). Now an error is generated instead. Thanks to Benilton Carvalho (Universidade Estadual de Campinas, Sao Paulo, Brazil) and Malte Bismarck (Martin Luther University of Halle-Wittenberg) for reports. Version: 1.41.1 [2015-04-25] o MEMORY ERRORS: Native functions R_affx_GetCHPEntries() and R_affx_ReadCHP() had unbalanced PROTECT()/UNPROTECT(). Also, native R_affx_GetCHPGenotypingResults() had two non-PROTECT():ed usages of mkString(). Thanks to Tomas Kalibera at Northeastern University for reporting on this. Version: 1.41.0 [2015-04-16] o The version number was bumped for the Bioconductor devel version, which is now BioC v3.2 for R (>= 3.3.0). Version: 1.40.0 [2015-04-16] o The version number was bumped for the Bioconductor release version, which is now BioC v3.1 for R (>= 3.2.0). Version: 1.39.5 [2015-04-15] o ROBUSTNESS: Now readPgfEnv()/readPgf() validated 'indices', iff possible. o Now readPgfEnv()/readPgf() coerces some header fields to integers, iff they exists, specifically 'num-cols', 'num-rows', 'probesets', and 'datalines'. o BUG FIX: convertCel() on a CCG/v1 CEL file could give "Error in sprintf("GridCorner%s=%d %d\n" ... invalid format '%d' ...)". Added package test for convertCel(), but in this particular case it would not have cought it because it only happened for chip types of particular dimensions. Thanks to Malte Bismarck at UK Halle (Germany) for reporting on this. o CLEANUP: Package no longer gives readBin() warnings on "'signed = FALSE' is only valid for integers of sizes 1 and 2". o CLEANUP: Removed 'SystemRequirements: GNU make'. Version: 1.39.4 [2015-01-18] o ROBUSTNESS: 'GNU make' is a SystemRequirements (for now). o ROBUSTNESS: Did not seem to be needed, but package is now a good citizen and do library.dynlib.unload() when unloaded. o CLEANUP: Now using requireNamespace() instead of require(). o CLEANUP: Internal cleanup of native code. Version: 1.39.3 [2014-11-26] o BUG FIX: readPgf() and readPgfEnv() failed to read all units (probesets) on some systems. Extensive package tests have been added to test this and other cases. Thanks to Grischa Toedt at EMBL Germany for reporting on, troubleshooting, and helping out with patches for this bug. Version: 1.39.2 [2014-10-28] o BUG FIX: The range test of argument 'units' to readCdf() and readCdfQc() was never performed due to a typo, meaning it was possible to request units out of range. Depending on system this could result in either a core dump or random garbage read for the out of range units. o ROBUSTNESS: Added package system tests for out of range 'units' and 'indices' arguments for most read functions. Version: 1.39.1 [2014-10-26] o ROBUSTNESS: Now all methods gives an informative error message if zero elements are requested, i.e. via zero-length argument 'indices' or 'units' that is not NULL. Previously this case would access all values just like NULL does. o ROBUSTNESS: Now readCelRectangle() gives an informative error message if argument 'xrange' or 'yrange' is not of length two. o BUG FIX: readPgf() and readPgfEnv() would give an error if argument 'indices' was specifies as a double rather than as an integer vector. Version: 1.39.0 [2014-10-13] o The version number was bumped for the Bioconductor devel version, which is now BioC v3.1 for R (>= 3.2.0). Version: 1.38.0 [2014-10-13] o The version number was bumped for the Bioconductor release version, which is now BioC v3.0 for R (>= 3.1.1). Version: 1.37.2 [2014-09-28] o Minor modifications due to the move to GitHub. Version: 1.37.1 [2014-08-25] o CLEANUP: Removed R CMD check NOTEs that appeared in recent R versions. Version: 1.37.0 [2014-04-11] o The version number was bumped for the Bioconductor devel version, which is now BioC v2.15 for R (>= 3.1.0). Version: 1.36.0 [2014-04-11] o The version number was bumped for the Bioconductor release version, which is now BioC v2.14 for R (>= 3.1.0). Version: 1.35.3 [2014-02-28] o Same updates as in release v1.34.2. Version: 1.35.2 [2014-02-28] o Patches to Fusion SDK based on clang v3.4. Version: 1.35.1 [2014-02-27] o Same updates as in release v1.34.1. Version: 1.35.0 [2013-10-14] o The version number was bumped for the Bioconductor devel version. Version: 1.34.2 [2014-02-28] o CLEANUP: Removed unnecessary usage of ':::'. Version: 1.34.1 [2014-02-27] o BUG FIX: readCelUnits() could throw 'Error in vector("double", nbrOfCells * nbrOfArrays) : vector size cannot be NA. In addition: Warning message: In nbrOfCells * nbrOfArrays : NAs produced by integer overflow' when reading from a large number of arrays and/or a large number of units. Previously the limit of nbrOfCells*nbrOfArrays was .Machine$integer.max (=2147483647), whereas now it is .Machine$double.xmax (=1.797693e+308). Thanks to Damian Plichta at the Technical University of Denmark for reporting on this. Version: 1.34.0 [2012-10-14] o The version number was bumped for the Bioconductor release version, which is now BioC v2.13 for R (>= 3.0.0). Version: 1.33.4 [2013-09-23] o SPEEDUP/CLEANUP: Package now uses which() instead of whichVector() of 'R.utils'. Before R (< 2.11.0), which() used to be 10x slower than whichVector(), but now it's 3x faster. Version: 1.33.3 [2013-06-29] o Same updates as in release v1.32.3. Version: 1.33.2 [2013-05-25] o Same updates as in release v1.32.2. Version: 1.33.1 [2013-05-20] o Same updates as in release v1.32.1. Version: 1.33.0 [2013-04-03] o The version number was bumped for the Bioconductor devel version. o No updates. Version: 1.32.3 [2013-06-29] o BUG FIX: Since affxparser v1.30.2/1.31.2 (r72352; 2013-01-08), writeCdf() would incorrectly encode the unit types, iff the input 'cdf' argument specified them as integers, e.g. as done by writeCdf() for AffyGenePDInfo in aroma.affymetrix. More specifically, the unit type index would be off by one, e.g. an 'expression' unit (1) would be encoded as an 'unknown' unit (0) and so on. On the other hand, if they were specified by their unit-type names (e.g. 'expression') the encoding should still be correct, e.g. if input is constructed from readCdf() of affxparser. Thanks to Guido Hooiveld at Wageningen UR (The Netherlands) for reporting on this. o BUG FIX: Similarily, writeCdf() has "always", at least affxparser v1.7.4 since (r21888; 2007-01-09), encoded unit directions and QC unit types incorrectly, iff they were specified as integers. Version: 1.32.2 [2013-05-25] o SPEEDUP: Removed all remaining gc() calls. o SPEEDUP: Replaced all rm() calls with NULL assignments. Version: 1.32.1 [2013-05-20] o CRAN POLICY: Now all Rd \usage{} lines are at most 90 characters long. Version: 1.32.0 [2013-04-03] o The version number was bumped for the Bioconductor release version. o No updates. Version: 1.31.4 [2013-03-19] o Made example(invertMap) a bit faster so 'R CMD check' won't complain. Version: 1.31.3 [2013-03-18] o CLEANUP: Internal isPackageLoaded() of findFiles() no longer uses defunct manglePackageName() function. Version: 1.31.2 [2013-01-07] o Same updates as in release v1.30.2. Version: 1.31.1 [2012-10-18] o Now compareCdfs() gives a more precise 'reason' attribute when there is a difference in (regular or QC) units. It narrows down the first unit that differs and reports it unit number. Version: 1.31.0 [2012-10-01] o The version number was bumped for the Bioconductor devel version. Version: 1.30.2 [2013-01-07] o BUG FIX: writeCdf() did not encode unit types as decoded by readCdf(). Unit type 'unknown' was incorrectly encoded such that readCdf() would decode it as 'copynumber'. Also, unit types 'genotypingcontrol' and 'expressioncontrol' where not encoded at all. Version: 1.30.0 [2012-10-01] o The version number was bumped for the Bioconductor release version. o No updates. Version: 1.29.13 [2012-09-26] o Added argument 'cdf=FALSE' to createCel(). Note, the previous implementation corresponded to cdf=TRUE. o ROBUSTNESS: Now createCel() validates/sets CEL header field 'total' based on 'cols' and 'rows'. o ROBUSTNESS: Added a system test for validating that the package can write and read a CEL. The test is spawning of another R process so that the test is robust against core dumps. o Bumped up package dependencies. Version: 1.29.12 [2012-09-12] o DOCUMENTATION: Updated one Rd link. Version: 1.29.11 [2012-09-01] o Added argument 'aliases' to arrangeCelFilesByChipType(), e.g. arrangeCelFilesByChipType(..., aliases=c("Focus"="HG-Focus")). o BUG FIX: arrangeCelFilesByChipType(pathnames) assumed 'pathnames' were files in the current directory. Version: 1.29.10 [2012-08-29] o Updated some internal files used solely for maintainance. Version: 1.29.9 [2012-08-29] o BUG FIX: The move to Fusion SDK 1.1.2 caused the package to not compile on Windows. Version: 1.29.8 [2012-08-14] o Upgraded to Fusion SDK 1.1.2. Version: 1.29.7 [2012-08-14] o Rearranged patchdir. Version: 1.29.6 [2012-06-26] o Same updates as in v1.28.1. Version: 1.29.5 [2012-06-19] o Added arrangeCelFilesByChipType() for moving CEL files to subdirectories named according to their chip types, which can be useful when for instance downloading GEO data sets. Version: 1.29.4 [2012-06-14] o readPgfEnv(..., indices=NULL) no longer gives a warning. o Updated the error messages for the CLF and PGF parsers. Version: 1.29.3 [2012-05-22] o Now system test tests/testWriteAndReadEmptyCdf.R generates an error that is detected and reported by R CMD check. Version: 1.29.2 [2012-05-22] o GENERALIZATION: Now system tests that launch another R process no longer assumes R is on the OS's search path. o ROBUSTNESS/CRAN POLICY: readCel() and readCelUnits() are no longer calling .Internal(qsort(...)). Version: 1.29.1 [2012-05-18] o Replaced several throw() with stop(), because the former assumes that R.methodsS3 is loaded, which it may not be. o ROBUSTNESS: Added a system test for validating that the package can write and read a CDF. The test is spawning of another R process so that the test is robust against core dumps. Version: 1.29.0 [2012-03-30] o The version number was bumped for the Bioconductor devel version. Version: 1.28.1 [2012-06-26] o COMPATIBILITY: Now package compile also with gcc/g++ 4.7. Thanks Dan Tenenbaum at the Bioconductor Core Team), Fred Hutchinson Cancer Research Center, USA for this. Version: 1.28.0 [2012-03-30] o The version number was bumped for the Bioconductor 2.10 release version. Version: 1.27.5 [2012-03-19] o ROBUSTNESS: Now the native code throws R errors, instead of printing an error message to stdout/stderr and then returning null, that is translated to errors at the R level. Version: 1.27.4 [2012-03-05] o BUG FIX: affxparser would not build on Windows with the new Rtools toolchain (Rtools 2.15.0.1915-1919). Version: 1.27.3 [2011-11-18] o ROBUSTNESS: Added sanity checks asserting that the internal readers did indeed read something and not just returned NULL. It should be very unlikely that this occurs, but there is still a small risk that after asserting that a file exists, but before the internal Fusion SDK parsers access the file, the file has been removed. Version: 1.27.1 [2011-11-01] o Same updates as in v1.26.1. Version: 1.27.0 [2011-10-31] o The version number was bumped for the Bioconductor devel version. Version: 1.26.4 [2012-03-06] o BUG FIX: affxparser would not build on Windows with the new Rtools toolchain (Rtools 2.15.0.1915-1919), which is for R (> 2.14.1), i.e. also for R v2.14.2 (but not v2.14.1). This is the same bug fix that was first done in v1.27.4. Version: 1.26.2 [2011-11-16] o The version number was bumped by Bioconductor to trigger a build. Version: 1.26.1 [2011-11-01] o FIX: Fixed warning on "In readBin(con, what = "integer", size = 4, n = 1, signed = FALSE, 'signed = FALSE' is only valid for integers of sizes 1 and 2" that some read methods would generated. Version: 1.26.0 [2011-10-31] o The version number was bumped for the Bioconductor 2.9 release version. Version: 1.25.1 [2011-09-27] o Maintainer email was updated. Version: 1.25.0 [2011-04-13] o The version number was bumped for the Bioconductor devel version. Version: 1.24.0 [2011-04-13] o The version number was bumped for the Bioconductor 2.8 release version. Version: 1.23.3 [2011-02-22] o DOCUMENTATION: Added a section on what it means by setting a new (different) chip type for the output in convertCel(). o ROBUSTNESS/BUG FIX: The internal .unwrapDatHeaderString(), used by convertCel() among others, would throw "Internal error: Failed to extract 'pixelRange' and 'sampleName' from DAT header. They became identical: ..." in case the DAT header of the CEL file did not contain all fields. The function has now been updated to be more forgiving and robust so that missing values are returned for such fields instead. Version: 1.23.2 [2011-02-15] o DOCUMENTATION: Added a clarification to the help page on 'Cell coordinates and cell indices' that the convention in affxparser is to use one-based cell indices, because they are more convenient to use in R. In order to clearly distinguish these from the redudant zero-based index values that also exist in CDF file, an additional section was added on that topic. Moreover, help pages for methods querying CDF files are now referring to the above page, where applicable. Thanks to William Mounts (Pfizer) and Todd Allen for pointing out these ambiguities in the documentation. Version: 1.23.1 [2010-12-16] o ROBUSTNESS: Now matrix(...) is used instead of .Interal(matrix(...)). Version: 1.23.0 [2010-10-17] o The version number was bumped for the Bioconductor devel version. Version: 1.22.0 [2010-10-17] o The version number was bumped for the Bioconductor 2.7 release version. Version: 1.21.1 [2010-10-05] o Now readCdfDataFrame() also returns the cell field 'expos'. Version: 1.21.0 [2010-04-22] o The version number was bumped for the Bioconductor devel version. Version: 1.20.0 [2010-04-22] o The version number was bumped for the Bioconductor 2.6 release version. Version: 1.19.6 [2010-02-11] o More fixes. Version: 1.19.5 [2010-02-09] o More fixes. Version: 1.19.4 [2010-02-06] o More fixes. Version: 1.19.3 [2010-02-06] o A couple of patches to Fusion SDK courtesy of Brian Ripley; they are needed for Windows (64). Version: 1.19.2 [2010-02-02] o A fix to the Windows build. Version: 1.19.1 [2010-01-29] o Updated Fusion SDK to 1.1.0. Version: 1.19.0 [2009-10-27] o Devel version bumped because of the new Bioconductor release. Version: 1.18.0 [2009-10-27] o Release version bumped because of the new Bioconductor 2.5 release. Version: 1.17.5 [2009-09-22] o Fixed broken link in an Rd file. Version: 1.17.4 [2009-09-21] o Added parseDatHeaderString(), which in combination with readCelHeader() can be used to infer the timestamp in the header of a CEL file. Version: 1.17.3 [2009-05-29] o Added applyCdfGroupFields() and cdfSetDimension(). Version: 1.17.2 [2009-02-20] o BUG FIX: readChp() would crash (segmentation fault) for (at least) some CHP files for GenomeWideSNP_5 generated by Affymetrix Power Tools. o BUG FIX: Updated compareCels() to work with new readCelHeader(). Version: 1.17.1 [2009-05-09] o Now readCelHeader() also reads DAT headers from Calvin CEL files. Version: 1.17.0 [2009-04-20] o Devel version bumped because of the new Bioconductor release. Version: 1.16.0 [2009-04-20] o Release version bumped because of the new Bioconductor 2.4 release. Version: 1.15.6 [2009-02-20] o Added optional argument 'newChipType' to convertCel() for overriding the default chip type. Useful for updating the formal chip type of old CEL files. o Removed all gc() calls in convertCel(). Version: 1.15.5 [2009-02-14] o Fixed a bug related to SET_VECTOR_ELT/SET_ELEMENR used on strings. Affected readChp. o Fixed a bug related to naming of the list structures (we assigned a list instead of a character as the name. Affected readCdfUnits and readCdfCellIndices. o Updated Fusion from 1.11 to 1.12. o Fixed a bug in the example for readCdfUnitsWriteMap: the package AffymetrixDataTestFiles was misspelled, so the tests were never run. Version: 1.15.4 [2009-02-10] o readCcg() and readCcgHeader() no longer give warnings on 'truncating string with embedded nul' in rawToChar(). These warnings made no difference, but were annoying. Version: 1.15.3 [2009-01-22] o Fixed a minor Rd problem. Version: 1.15.2 [2008-12-30] o Same bug fix as in release version v1.14.2. Version: 1.15.1 [2008-12-04] o Same bug fix as in release version v1.14.1. Version: 1.15.0 [2008-10-21] o Devel version bumped because of the new Bioconductor release. Version: 1.14.2 [2008-12-30] o BUG FIX: readChp() would not read all data. Thanks Gabor Csardi for reporting this and providing a patch. Version: 1.14.1 [2008-12-04] o BUG FIX: When the CDF file is on a Windows network, that is, has a pathname starting with '//' or '\\', then the 'chiptype' reported by readCdfHeader() contains a path component as well. This seems to be due to a bug in Fusion SDK. Version: 1.14.0 [2008-10-21] o Release version bumped because of the new Bioconductor 2.3 release. Version: 1.13.8 [2008-08-28] o Fix of include statements in Fusion, details are described in inst/info/changes2fusion.txt. This fixes an issue with GCC 4.3 Version: 1.13.7 [2008-08-23] o SPEED UP: readCcg() is substantially faster after removing all gc() calls. Version: 1.13.6 [2008-08-21] o Updated Fusion SDK from 1.0.10b (Jan 2008) to 1.0.11 (July 2008). Version: 1.13.x [2008-08-14] o Fixed typos and incorrect equation in help page '2. Cell coordinates and cell indices'. Version: 1.13.5 [2008-08-09] o BUG FIX: writeCdf() would write 'CustomSeq' units as 'Tag' units, and vice versa. This means that *ASCII* CDFs containing such units and converted with convertCdf() would be have an incorrect unit type for these units. Also, unit type 'Copy Number' is reported as "copynumber" and no longer as "unknown". o BUG FIX: The increase of the internal buffer for reading the 'refseq' header field of ASCII CDFs that was done in v1.11.2 was mistakenly undone in v1.13.3. o Made readCdf() recognize more unit types. Version: 1.13.4 [2008-08-05] o Renamed the HISTORY file to NEWS. o Now help(createCel) (and its example) clarifies that the template CEL header can be of v3 (ASCII), v4 (binary;XDA), or v1 (binary;Calvin). Version: 1.13.3 [2008-05-20] o BUG FIX: Now writeTpmap works. Version: 1.13.2 [2008-05-08] o Copied all updates in v1.12.2 (release) to v1.13.2 (devel). Version: 1.13.1 [2008-05-02] o Copied all updates in v1.12.1 (release) to v1.13.1 (devel). Version: 1.13.0 [2008-04-29] o Devel version bumped because of the new Bioconductor release. Version: 1.12.2 [2008-05-09] o BUG FIX: v1.12.1 would not build on Windows. Fix by Martin Morgan. Version: 1.12.1 [2008-05-02] o Added readChp(). Contribution by Robert Gentleman. Version: 1.12.0 [2008-04-29] o Release version bumped because of the new Bioconductor 2.2 release. Version: 1.11.13 [2008-04-13] o Updated to Fusion SDK v1.0.10b. Version: 1.11.? [2008-03-06] o BUG FIX: Regular expression pattern 'a-Z' is illegal on (at least) some locale, e.g. 'C' (where 'A-z' works). The only way to specify the ASCII alphabet is to list all characters explicitly, which we now do in all methods of the package. See the r-devel thread "invalid regular expression '[a-Z]'" on 2008-03-05 for details. Version: 1.11.6 [2008-03-04] o Added trial versions of readClf() and readPgf(). Version: 1.11.5 [2008-02-29] o Updated cdfMergeStrands() to merge any even number of groups, not only units with two or four group pairs. o BUG FIX: The code in findFiles() for testing if R.utils is loaded or not was not correct making it fail to detect R.utils. Version: 1.11.4 [2008-02-20] o Now findFiles() and hence findCdf() is only utilizing the R.utils package if it is already loaded. It will no longer try to load R.utils. o Added argument 'allFiles=TRUE' to findFiles(). o Updated readCcg() according to the newer file format specifications. Now it is possible to do low-level reading of copy-number CNCHP files generated by the Affymetrix Genotype Console v2. Version: 1.11.3 [2007-12-01] o Removed argument 'reorder' from readCel() and readCelUnits() since its name was misleading (the returned value was identical regardless of 'reorder', but the reading speed was faster when 'reorder' was TRUE, which is how it is now hardwired). Version: 1.11.2 [2007-11-06] o BUG FIX: Reading a CDF that has a 'refseq' header field longer than 65,000 symbols would crash R, e.g. when reading certain CDFs for resequencing chip types. A buffer size internal of Fusion SDK was increased from 65,000 to 400,000 bytes. Thanks Wenyi Wang for reporting this. o BUG FIX: Argument 'verbose' of tpmap2bpmap() was not coerced to integer before passed to the native code. o TYPO FIX: The internal .initializeCdf(), used when creating new CDFs, had an error message refering to an invalid 'qcUnitLengths' when it was supposed to be 'unitLengths'. Thanks Elizabeth Purdom for reporting this. o CLEAN UP: created a Makefile in /inst/info for comparing Fusion SDK with affxparser Version: 1.11.1 [2007-10-12] o BUG FIX: For some Calvin CEL files the CEL header does not contain "parent parameter" 'affymetrix-dat-header' but only parameter 'affymetrix-partial-dat-header'. In that case convertCel() would throw an error about 'sprintf("DatHeader=%s\n", datHeader)'. Now a "fake" DAT header is created from the partial one. If neither is found, a slightly more informative exception is thrown. o CLEAN UP: convertCel() will no longer generate a warning if the corresponding CDF file was not found. Version: 1.11.0 [2007-10-02] o Version bumped because of the new Bioconductor release. Version: 1.9.5 [2007-09-16] o Added argument 'recursive=TRUE' to findCdf(). Note, the current working directory is always scanned first, but never recursively (unless explicitly added to the search path). This is to avoid "endless" scans in case the search path has not been set. o findFiles() now do a breath-first search in lexicographic order. o Removed default search paths cdf/ and data/cdf/. We do not want to enforce a standard path. o Now the examples (as well as test scripts) utilize data available in the new Bioconductor AffymetrixDataTestFiles package. This means that R CMD check now runs much more tests, which is good. o CLEAN UP: Removed many of the old testscripts/ scripts. They are now under tests/. o BUG FIX: findFiles() was not robust against broken Unix links. o BUG FIX: If the destination file already existed, convertCel() would correctly detect that, but would report the name of the source file. Version: 1.9.4 [2007-08-25] o Updated to Fusion SDK v1.0.9. Version: 1.9.3 [2007-08-16] o See updated made to release v1.8.3 below. o The only difference between v1.9.3 and v1.8.3 is the modification of findCfd() in v1.9.2. Version: 1.9.2 [2007-07-27] o This BioC devel version requires R v2.6.0 due to a change of how strings are handled in C by BioC. o Modified findCdf() such that it is possible to set an alternative function for how CDFs are located. Version: 1.8.3 [2007-08-16] (also added to devel v1.9.3) o Made several updated so that affxparser better supports CEL files in the new Command Console (Calvin) file format: - isCelFile() recognized Calvin CEL files. - convertCel() can convert a Calvin CEL files into v4 CEL files. - writeCelHeader() can write v4 CEL headers given Calvin CEL header. o Added internal/private function to read Command Console Generic (CCG) files, also known as Calvin files. Note, these functions are currently *not* utilizing the Fusion SDK library, but are instead written from scratch based on the Affymetrix' file format definitions. Version: 1.8.2 [2007-08-01] None of the fixes changes the API/function of the BioC release version: o Optimized writeCdfHeader() for memory. For a CDF with 1,200,000+ units just writing the unit names would consume 1-1.5GB RAM. Now it writes unit names in chunks keeping the memory overhead around 100-200MB. o Made convertCdf() more memory efficient. o BUG FIX: The error message in isCelFile() when the file was not found was broken. Version: 1.8.1 [2007-07-26] o Now affxparser install on OSX with PPC. Version: 1.8.0 [2007-04-24] o The version number was bumped up with the Bioconductor release. Version: 1.7.5 [2007-03-08] o Added argument 'truncateGroupNames' to readCdfGroupNames() which defaults to TRUE for backward compatibility. When TRUE, any prefix of group names identical to the unit name will be stripped of the group names. Version: 1.7.4 [2007-02-21] o Now readCelUnits() can handle unit groups for which there are no probes, e.g. when stratifying on PM in a unit containing only MMs. o Added writeCdfHeader(), writeCdfQcUnits() and writeCdfUnits(). These are all used by writeCdf(). They also make it possible to write a CDF in chunks in order to for instance convertCdf() in constant memory. Version: 1.7.3 [2007-01-05] o Added cdfAddPlasqTypes(). o Now readCdfUnits(..., readDirections=TRUE) also returns group directions. o Now readCdf() reads all unit and group fields by default. o In addition to optimizing IO time, read maps can be used to unrotate CEL data rotated by the dChip software. For more information, see help on "Cell-index maps for reading and writing". o BUG FIX: Using read maps for readCel() would give an error saying the read map is invalid even when it is not. Version: 1.7.2 [2006-12-10] o BUG FIX: readCdfUnits() and readCdfCellIndices() with stratifyBy="mm" would return the same as stratifyBy="pm". Options "pm" and "pmmm" are unaffected by this fix. o Added argument 'isPm' to readCdf(). Version: 1.7.1 [2006-11-03] o Updated to Fusion SDK v1.0.8. o BUG FIX: In Fusion SDK (v1.0.5) that previous version of affxparser used, a CDF file was never closed on Unix platforms (this bug was not in the Windows version). Since Fusion allocated memory for the complete CDF (even if a subset is only read), this caused the memory usage to blow up, when reading the same or different CDF files multiple times, because the memory was never deallocated. Thanks Seth Falcon and Ken Simpson for reporting this problem. o Windows build change: The Windows version is building against the Windows code of Fusion SDK not the POSIX code. In order to do this we have had to patch the preprocessor code in several of the Fusion SDK source-code files, which has to be redone manually whenever Fusion is updated. Starting with this version, we instead set the _MSC_VER flag used in the Fusion code to indicate Windows (set by the Microsoft Visual C++ compiler). Since we are using MINGW this flag is obviously not set. Faking _MSC_VER this way leaves us only having to patch one single file in the Fusion release instead of 10-20. Hopefully there are no other side effects. Version: 1.7.0 [2006-10-25] o BUG FIX: writeCdf() would create an invalid CDF file if there were no QC units. This would in turn make readCdfUnits() etc core dump. o BUG FIX: Similar to get bug fix in the C code for readCelHeader(), much of the C-level code for CDF (and BPMAP) files assumes that the strings from Fusion SDK have a null terminator. At least for CDF unit names, this is not necessarily the case. To be on the safe side, for all retrieved Fusion SDK strings we now make sure there is a null terminator before converting it into an R string. Thanks to Ken Simpson at WEHI for all troubleshooting on this. o Because of the above bug fix, the ASCII mouse exon CDF can now be converted into a valid binary CDF. o Made readCelUnits() a bit more clever if a 'cdf' structure with only cell indices is passed. Then all fields are just indices and one can call unlist immediately. This speeds things up a bit. o The devel version number was bumped up with the Bioconductor release. Version: 1.6.0 [2006-10-03] o The version number was bumped up with the Bioconductor release. Version: 1.5.x [2006-09-21] o Now the package passes R CMD check without warnings. o BUG FIX: The C code for readCelHeader() did not allocate space for the string null terminator for the header elements that originates from wide C++ string. This caused readCelHeader() to contain string elements with random characters at the end. o BUG FIX: nrows and ncols were swapped in the CDF header when written by writeCdf(). This was missed because all tested CDFs were square. o Added compareCdfs() to verify that a converted CDF is correct. o Added convertCdf() utilizing the new writeCdf(). o Added trial version of createCel(). o Added trial version of updateCelUnits(). Version: 1.5.4 [2006-08-18] o Updated Fusion SDK to version 1.0.7. o BUG FIX: The new implementation of updateCel() utilizing raw vectors was not correct; extra zeros was written too. The example code of updateCel reveals such errors much easier now. o BUG FIX: updateCel() would in some cases give "Error: subscript out of bounds" when writing the last chunk. Version: 1.5.3 [2006-07-24] o Improved the speed of updateCel() substantially by first working with raw vector in memory and then write binary data to file. Data is also written in chunks (instead of all at once), to minimize the memory overhead of using raw vectors, which is especially important for the larger chips, e.g. 500K. o Added functional prototype of updateCel() to *update* binary (v4) CEL files. Currently, the code does make use the Fusion SDK. There is currently no writeCel() to create a CEL file from scratch. However, with the auxillary function copyCel() one can copy an existing CEL file and then update that one. Thus, it is now possible to write, say, normalized probe intensities to a CEL file. Note that this is only a first prototype and functions may change in a future release. Version: 1.5.2 [2006-05-31] o Updated Fusion SDK to version 1.0.6. Version: 1.5.1 [2006-05-15] o Updated Fusion SDK to version 1.0.5. o BUG FIX; Made small changes to the SDK to allow it to compile under Mac OS X with GCC-4.0.3 shipping with R-2.3.0 o Made changes to the Makevars, _Makefile and cmd_line scripts. Version: 1.5.0 [2006-05-12] o Cleaned up and restructured the help pages; several Rd pages are now made "internal" so they do not show up on the help index page. Instead they are accessable from within other help pages (if you browsing via HTML that is). Added a help page on common terms. o Added cdfOrderBy() and cdfOrderColumnsBy() for restructuring group fields in a CDF list structure. Added cdfGetGroups() too. o Added a bit more documentation on how to set the default CDF path. o BUG FIX: On Linux 64-bit read CEL intensities would all be zero. This was due to compiler settings in the Fusion SDK package, which is circumvented by gcc compile it with a lower optimization level. o BUG FIX: When argument 'cdf' was a CDF list structure with elements 'type' or 'direction', readCelUnits() would not read the correct cells because the values of 'type' and 'direction' would be included in the extracted list of cell indices. Version: 1.4.0 [2006-04-27] o The stable version for Bioconductor 1.8. Version: 1.3.3 [2006-04-15] o Updated the Fusion SDK to version 1.0.5 (an unofficial release). It now works on Solaris. o New method readCdfCellIndices(), which is a 5-10 times faster special-case implementation of readCdfUnits() to read cell indices only. o Now readCelUnits() sorts the cell indices before reading the data from each file. This minimizes the amount of jumping around in the CEL files resulting in a speed-up of about 5-10 times. o Renamed readCdfUnitsMap() to readCdfUnitsWriteMap(). o New method invertMap() for fast inversion of maps. o KNOWN BUGS: The weird bug as in v1.3.2 remains with the new Fusion SDK, R v2.3.0 beta (2006-04-10 r37715) on WinXP. Internally readCdfCellIndices() replaces readCdfUnits(), but the error is still the same. Version: 1.3.2 [2006-03-28] o All cell and unit indices are now starting from one and not from zero. This change requires that all code that have been using a previous version of this package have to be updated! o Further optimization in speed and memory for most methods. o New methods readCelRectangle() to read probe signals from a specify area of the chip. o Added extensive help on cell coordinates and cell indices as well read and write maps. o KNOWN BUGS: At least on WinXP, heavy use of readCelUnits() will sooner or later core dump R; it seems to be a memory related from that occur when reading the CDF and extracting the name of the unit. However, when "torturing" readCdfUnits() the crash won't happen so it might be that readCel() does something. Have not tried on other platforms. Version: 1.3.1 o ...