metagenomeSeq

DOI: 10.18129/B9.bioc.metagenomeSeq    

Statistical analysis for sparse high-throughput sequencing

Bioconductor version: Release (3.6)

metagenomeSeq is designed to determine features (be it Operational Taxanomic Unit (OTU), species, etc.) that are differentially abundant between two or more groups of multiple samples. metagenomeSeq is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations.

Author: Joseph Nathaniel Paulson, Nathan D. Olson, Justin Wagner, Hisham Talukder, Mihai Pop, Hector Corrada Bravo

Maintainer: Joseph N. Paulson <jpaulson at jimmy.harvard.edu>

Citation (from within R, enter citation("metagenomeSeq")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("metagenomeSeq")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("metagenomeSeq")

 

PDF R Script fitTimeSeries: differential abundance analysis through time or location
PDF R Script metagenomeSeq: statistical analysis for sparse high-throughput sequencing
PDF   Reference Manual
Text   NEWS

Details

biocViews Classification, Clustering, DifferentialExpression, GeneticVariability, Metagenomics, Microbiome, MultipleComparison, Normalization, Sequencing, Software, Visualization
Version 1.20.1
In Bioconductor since BioC 2.12 (R-3.0) (5 years)
License Artistic-2.0
Depends R (>= 3.0), Biobase, limma, glmnet, methods, RColorBrewer
Imports parallel, matrixStats, foreach, Matrix, gplots
LinkingTo
Suggests annotate, BiocGenerics, biomformat, knitr, gss, testthat (>= 0.8), vegan, interactiveDisplay
SystemRequirements
Enhances
URL https://github.com/nosson/metagenomeSeq/
BugReports https://github.com/nosson/metagenomeSeq/issues
Depends On Me etec16s, metavizr, msd16s
Imports Me metagenomeFeatures
Suggests Me curatedMetagenomicData, interactiveDisplay, phyloseq
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package metagenomeSeq_1.20.1.tar.gz
Windows Binary metagenomeSeq_1.20.1.zip
Mac OS X 10.11 (El Capitan) metagenomeSeq_1.20.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/metagenomeSeq
Package Short Url http://bioconductor.org/packages/metagenomeSeq/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.6 Source Archive

Documentation »

Bioconductor

R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: