************************************************** * * * SSPA NEWS * * * ************************************************** CHANGES IN SSPA VERSION 1.99.0 NEW FEATURES o Added new estimation method for the density of effect sizes and proportion of non differentially expressed genes o power and sample size analysis can now also be performed for experimental designs that lead to F and \chi^2 statistics e.g. RNAseq data BUG FIXES o suppressWarings from dt or pt when ncp is large CHANGES IN SSPA VERSION 1.5.1 NEW FEATURES o Accessor functions for both PilotData and SampleSize class o Added Nutrigenomics data for use in examples o Updated the citation o Updated the vignette o Plots produced by the packages are now using the lattice packages BUG FIXES o replaced call .C("massdist", ... package="stats") to .C("massdist", ... package="sspa") CHANGES IN SSPA VERSION 1.5.0 NEW FEATURES o Added Student t distribution as distribution for non-differentially expressed genes o Added moderated version of the Student t distribution for more reliable results when using SSPA in combination with limma o Better upper bound estimates for pi0 taken from Efron et al. (2001) Empirical Bayes Analysis of a Microarray Experiment. o Replaced FFT derived characteristic function by analytical expression for the characteristic functions both normal and Student t BUG FIXES o In function Power(): corrected the effective sample size if user defined o Figure captions in vignette modified