Inferring tumor-specific cancer dependencies through integrating
ex-vivo drug response assays and drug-protein profiling
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Documentation for package ‘DepInfeR’ version 1.12.0
Help Pages
| DepInfeR-package | DepInfeR for inferring sample-specific protein dependencies |
| drug_response_GDSC | drug_response_GDSC |
| mutation_GDSC | mutation_GDSC |
| processTarget | Function for pre-processing drug-protein affinity dataset |
| responseInput | responseInput |
| runLASSORegression | Main function for running LASSO regression to calculate protein dependence coefficient |
| targetInput | targetInput |
| targetMatrix | targetMatrix |
| targetsGDSC | targetsGDSC |