Combination Connectivity Mapping


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Documentation for package ‘ccmap’ version 1.30.0

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get_dprimes Extract unbiased effect sizes from meta-analysis by crossmeta.
query_combos Get overlap between query and predicted drug combination signatures.
query_drugs Get correlation between query and drug signatures. Determines the pearson correlation between the query and each drug signature. Drugs with the largest positive and negative pearson correlation are predicted to, respectively, mimic and reverse the query signature. Values range from +1 to -1.
sum_rowcolCumsum Sum of cumulative sum computed over rows then columns of matrix.