Analysis of patient-derived xenograft (PDX) data


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Documentation for package ‘Xeva’ version 1.18.0

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ABC area between curves Computes the area between two time-volume curves.
addExperimentalDesign Add a new experimental design
addExperimentalDesign-method Add a new experimental design
angle compute angle Computes the angle between two time-volume curves.
AUC area under the curve 'AUC' Returns area under the curve
batchInfo Get batch information
batchInfo-method Get batch information
brca PDXE breast cancer dataset
createXevaSet XevaSet constructor
dosePlot plot dose data
downloadXevaSet Download a XevaSet object or table of available XevaSet objects
drugInform Get drug information Get the drug information slot from a XevaSet object.
drugInform-method Get drug information Get the drug information slot from a XevaSet object.
drugSensitivitySig get drug sensitivity values
getExperiment Get PDX experiment data
getExperiment-method Get PDX experiment data
getMolecularProfiles Get molecular profiles from a XevaSet object
lmm linear mixed model
modelInfo modelInfo Generic Generic for modelInfo method
modelInfo-method modelInfo Generic Generic for modelInfo method
mRECIST Computes the mRECIST
PDXMI PDX-MI data
plotBatch Plot batch data
plotmRECIST To plot mRECIST values
plotPDX Plot batch data
print.batchResponse Print the batch response
print.modelResponse Print the model response
print.pdxBatch Print the pdx batch
repdx Example PDX dataset
response compute PDX response
selectModelIds To select model IDs based on drug name and/or tissue type.
selectModelIds-method To select model IDs based on drug name and/or tissue type.
sensitivity Get sensitivity for an Xeva object
setResponse set PDX response
slope Computes slope
subsetXeva Subset Xeva object.
summarizeMolecularProfiles Summarize molecular profiles
summarizeResponse Summarize Response of PDXs
TGI tumor growth inhibition (TGI) Computes the tumor growth inhibition (TGI) between two time-volume curves
waterfall waterfall plot Creates waterfall plot for a given drug.