RITAN indexes multiple resources and choosing which of them are most relevant for your study can be a challenge. To help with this process, we provide below a set of examples from different types of studies and the thinking behind which resources were used.
library(RITANdata) library(RITAN) library(knitr) kable( attr(network_list, 'network_data_sources') ) kable( sapply(geneset_list, length), col.names = c('# Genesets') )
While many resources contain information about protein complexes (obligate interactions) and protein-protein interactions (often transient), some use experimental techniques that are specific for physical ineractions. Determining whihc resources indicate physical, through-metabolite, and through-DNA (i.e. transcription factors) interactions, we recommend: 1) each resource’s primary publication 2) the pathguide website 3) the following guidelines