DOI: 10.18129/    

This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

This package is for version 3.14 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see alsace.

ALS for the Automatic Chemical Exploration of mixtures

Bioconductor version: 3.14

Alternating Least Squares (or Multivariate Curve Resolution) for analytical chemical data, in particular hyphenated data where the first direction is a retention time axis, and the second a spectral axis. Package builds on the basic als function from the ALS package and adds functionality for high-throughput analysis, including definition of time windows, clustering of profiles, retention time correction, etcetera.

Author: Ron Wehrens

Maintainer: Ron Wehrens <ron.wehrens at>

Citation (from within R, enter citation("alsace")):


To install this package, start R (version "4.1") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



PDF alsace
PDF   Reference Manual
Text   NEWS


biocViews Software
Version 1.30.0
In Bioconductor since BioC 2.14 (R-3.1) (8 years)
License GPL (>= 2)
Depends R (>= 2.10), ALS, ptw (>= 1.0.6)
Suggests lattice, knitr
Depends On Me
Imports Me tofsims
Suggests Me
Links To Me
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Source Package alsace_1.30.0.tar.gz
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