RTN: Reconstruction of Transcriptional regulatory Networks and analysis of regulons


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Documentation for package ‘RTN’ version 2.16.0

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RTN-package Reconstruction and Analysis of Transcriptional Networks.
AVS-class Class '"AVS"': an S4 class for variant set enrichment analysis.
avs.evse An eQTL/VSE pipeline for variant set enrichment analysis.
avs.evse-method Class '"AVS"': an S4 class for variant set enrichment analysis.
avs.get Get information from individual slots in an AVS object.
avs.get-method Class '"AVS"': an S4 class for variant set enrichment analysis.
avs.pevse An EVSE pipeline using precomputed eQTLs.
avs.pevse-method Class '"AVS"': an S4 class for variant set enrichment analysis.
avs.plot1 Plot results from AVS methods, single plots.
avs.plot2 Plot results from AVS methods, multiple plots.
avs.rvse An rQTL/VSE pipeline for variant set enrichment analysis.
avs.rvse-method Class '"AVS"': an S4 class for variant set enrichment analysis.
avs.vse Variant set enrichment (VSE) analysis.
avs.vse-method Class '"AVS"': an S4 class for variant set enrichment analysis.
pksData Pre-processed datasets for the RTN package.
RTN Reconstruction and Analysis of Transcriptional Networks.
stni A pre-processed TNI for demonstration purposes only.
tfsData Pre-processed datasets for the RTN package.
TNA-class Class '"TNA"': an S4 class for Transcriptional Network Analysis.
tna.get Get information from individual slots in a TNA object.
tna.get-method Class '"TNA"': an S4 class for Transcriptional Network Analysis.
tna.gsea1 One-tailed Gene Set Enrichment Analysis (GSEA) over a list of regulons.
tna.gsea1-method Class '"TNA"': an S4 class for Transcriptional Network Analysis.
tna.gsea2 Two-tailed Gene Set Enrichment Analysis (GSEA) over a list of regulons.
tna.gsea2-method Class '"TNA"': an S4 class for Transcriptional Network Analysis.
tna.mra Master Regulator Analysis (MRA) over a list of regulons.
tna.mra-method Class '"TNA"': an S4 class for Transcriptional Network Analysis.
tna.plot.gsea1 Plot enrichment analyses from TNA objects.
tna.plot.gsea2 Plot enrichment analyses from TNA objects.
tnaData Pre-processed datasets for the RTN package.
TNI-class Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.alpha.adjust Adjust the significance level for two datasets.
tni.annotate.regulons Annotate regulons with external gene set collections.
tni.annotate.regulons-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.annotate.samples Annotate samples with external gene set collections.
tni.annotate.samples-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.area3 Compute regulon activity by calling aREA (analytic Rank-based Enrichment Analysis) algorithm
tni.area3-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.bootstrap Inference of consensus transcriptional networks.
tni.bootstrap-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.conditional Modulators of transcription factor (TF) activity assessed by conditional mutual information analysis.
tni.conditional-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.constructor A constructor for objects of class TNI.
tni.dpi.filter Data Processing Inequality (DPI) filter.
tni.dpi.filter-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.get Get information from individual slots in a TNI object.
tni.get-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.graph Compute a graph from TNI objects.
tni.graph-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.gsea2 Compute regulon activity by calling GSEA2 (two-tailed Gene Set Enrichment Analysis) algorithm
tni.gsea2-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.overlap.genesets Associate regulons with external gene set collections.
tni.overlap.genesets-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.permutation Inference of transcriptional networks.
tni.permutation-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.plot.checks Plot regulon target counts.
tni.plot.sre Plot Subgroup Regulon Enrichment for TNI-class objects.
tni.preprocess A preprocessing function for objects of class TNI.
tni.preprocess-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.prune Prune regulons to remove redundant targets for regulon activity analysis
tni.prune-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.regulon.summary Summary of regulon characteristics.
tni.regulon.summary-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.replace.samples Entry point to assess new samples with previously calculated regulons.
tni.replace.samples-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni.sre Subgroup Regulon Enrichment for TNI-class objects.
tni.sre-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tni2tna.preprocess A preprocessing function for objects of class TNI.
tni2tna.preprocess-method Class '"TNI"': an S4 class for Transcriptional Network Inference.
tniData Pre-processed datasets for the RTN package.
upgradeTNA Upgrade objects of class TNI.
upgradeTNI Upgrade objects of class TNI.