Bioconductor components for general cancer genomics


[Up] [Top]

Documentation for package ‘BiocOncoTK’ version 1.12.1

Help Pages

add_sym add symbols in rowData to a SummarizedExperiment that has Entrez IDs for rownames
annotTabs table names in Annotated pancancer data release
bindMSI bind MSI data to a SummarizedExperiment
bipg_tests configure a bipartite graph relating tumor type to gene, using graphNEL
brcaMAE a virtual MultiAssayExperiment for pancancer-atlas BRCA data
buildPancanSE helper for SummarizedExperiment construction from pancan
CCLE_DRUG_BROAD CCLE_DRUG_BROAD: serialization of legacy CCLE 'Drug data' from Broad Institute
cell_70138 cell_70138: a table with cell-line information from LINCS
clueDemos generate lists to generate clue API queries
clueServiceNames Provide names of some clue.io services for which examples are available in this package.
darmGBMcls Data in count_lstpm format from Darmanis 2017 (PMC 5810554) single cell RNA-seq in GBM
dingMSI microsatellite instability data in TCGA, collected from Ding et al. Cell 173(2) 2018.
featIDMapper define assay-specific feature names in a character vector
fireMSI microsatellite instability data in TCGA, collected from curatedTCGAData
get_plates use curatedTCGAData request to acquire plate codes for samples
ggFeatDens create ggplot for density of starts of a GRanges in an interval
ggFeatureSegs generate a ggplot of segments of gene-like regions
ggMutDens make a ggplot with density traces of mutations per base pair, for 'most mutated' tumor types in a given interval
icd10_c helper for interpreting ICD-10 codes
k23sig a table of 'significant' MSIsensor-score/expression relationships in TCGA
kang_DNArepair list of 151 genes annotated as DNA repair pathway members
loadPatel use BiocFileCache discipline to acquire patelGBMSC SummarizedExperiment
load_ccleNRAS utilities for mock data (not involving internet access for vignette)
load_nrasdf utilities for mock data (not involving internet access for vignette)
load_NRAS_AHR utilities for mock data (not involving internet access for vignette)
log10pl1 log10(x+p) transformation for use with scales/ggplot2
map_tcga_ncit a manually constructed table mapping TCGA acronyms to NCIT thesaurus tags
mc3toGR create a GRanges from the MC3 mutation data
molpo_3utr representation of 3'UTR MSI events in TCGA from Cortes-Ciriano et al. 2017
molpo_5utr representation of 5'UTR MSI events in TCGA from Cortes-Ciriano et al. 2017
molpo_CDS representation of MSI events in coding regions TCGA from Cortes-Ciriano et al. 2017
molpo_WGS representation of events detected in 708 WGS experiments TCGA from Cortes-Ciriano et al. 2017
MSIsensor.10k MSIsensor microsatellite instability scores for TCGA, collected from Ding et al. Cell 173(2) 2018.
multiviz visualize aspects of MSIsensor/expression relationships
oncoPrintISB interactive interface to ComplexHeatmap oncoPrint with inputs from ISB Cancer Genomics Cloud BigQuery back end
pancan.clin.varnames pancan.clin.varnames: a data.frame with a list of variable names for clinical patient data
pancan_app provide a shiny app to 'glimpse' structure and content of pancan atlas
pancan_BQ provide bigrquery connection to pancancer Annotated datasets
pancan_clinicalTabVarnames give an interface to tablenames
pancan_longname utility to help find long table names
pancan_sampTypeMap helper for interpreting pancan-atlas sample type codes
pancan_tabulate tabulate a variable in a table
patient_to_tumor_code data.frame mapping from TCGA patient_barcode to TCGA tumor code
pertClasses enumerate perturbagen classes
pert_70138 pert_70138: a table with perturbagen information from LINCS
query_clue run the api.clue.io API to acquire information on LINCS experiments
replaceRownames map rownames of an SE to another vocabulary
small_msi filtered MSI data for demonstrating exploratory app
TcgaMutCounts obtain data frame with counts of mutation per gene symbol for selected tumor type
TcgaNIndWithAnyMut Give count of individuals with a mutation recorded for selected tumor
tumNorSet create list with SEs for tumor and normal for a tumor/assay pairing
viz_msi_raw small app to survey MSIsensor against expression