COMPASS

DOI: 10.18129/B9.bioc.COMPASS    

This package is for version 3.11 of Bioconductor; for the stable, up-to-date release version, see COMPASS.

Combinatorial Polyfunctionality Analysis of Single Cells

Bioconductor version: 3.11

COMPASS is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. COMPASS uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.

Author: Lynn Lin, Kevin Ushey, Greg Finak, Ravio Kolde (pheatmap)

Maintainer: Greg Finak <gfinak at fhcrc.org>

Citation (from within R, enter citation("COMPASS")):

Installation

To install this package, start R (version "4.0") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("COMPASS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("COMPASS")

 

HTML R Script COMPASS
PDF R Script SimpleCOMPASS
PDF   Reference Manual
Text   NEWS

Details

biocViews FlowCytometry, ImmunoOncology, Software
Version 1.26.0
In Bioconductor since BioC 2.14 (R-3.1) (6.5 years)
License Artistic-2.0
Depends R (>= 3.0.3)
Imports methods, Rcpp, data.table, RColorBrewer, scales, grid, plyr, knitr, abind, clue, grDevices, utils, pdist, magrittr, reshape2, dplyr, tidyr, rlang, BiocStyle, rmarkdown
LinkingTo Rcpp (>= 0.11.0)
Suggests flowWorkspace(>= 3.33.1), flowCore, ncdfFlow, shiny, testthat, devtools, flowWorkspaceData, ggplot2
SystemRequirements
Enhances
URL
BugReports https://github.com/RGLab/COMPASS/issues
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package COMPASS_1.26.0.tar.gz
Windows Binary COMPASS_1.26.0.zip (32- & 64-bit)
macOS 10.13 (High Sierra) COMPASS_1.26.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/COMPASS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/COMPASS
Package Short Url https://bioconductor.org/packages/COMPASS/
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