Data preprocessing and quality control for Illumina HumanMethylation450 and MethylationEPIC BeadChip


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Documentation for package ‘ENmix’ version 1.25.1

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B2M Convert methylation beta value to M value.
calcdetP To calculate detection P values
combp Identification of differentially methylated regions
ctrlsva Non-negative internal control surrogate variables
dupicc Evaluations of methylation duplicates
estimateCellProp Cell type proportion estimation
freqpoly Frequency polygon plot
getB Extract methylation Beta values.
getCGinfo CpG probe annotation inforamtion
getmeth Create a methDataSet
ipdmr Differentially methylated region finder using interval P values
M2B Convert methylation M value to methylation beta value.
methDataSet Class '"methDataSet"'
methDataSet-class Class '"methDataSet"'
methyAge Methylation Age estimation
mhtplot P value manhattan plot
mpreprocess methylation QC and preprocessing pipeline for Illuminal arrays
multifreqpoly Frequency polygon plot
nmode.mc Estimating number of mode for each row of data
norm.quantile Quantile normalization.
normalize.quantile.450k Quantile normalization.
oxBS.MLE oxBS-MLE.
p.qqplot P value Q-Q plot
pcrplot Principal component regression plot
plotCtrl Internal control plot
predSex Estimating sample sex
preprocessENmix The ENmix background correction for HumanMethylation 450 and MethylationEPIC BeadChip
QCfilter Sample or CpG probe filter.
QCinfo QC information
rcp Regression on Correlated Probes(RCP)
readidat Parsing IDAT files from Illumina methylation arrays.
readmanifest Parsing Illumina methylation arrays manifest file.
relic RELIC dye bias correction method for Illumina HumanMethylation450 and MethylationEPIC BeadChip
rgDataSet Class '"rgDataSet"'
rgDataSet-class Class '"rgDataSet"'
rm.outlier Filtering out outlier and/or low quality values
show-method Class '"methDataSet"'
show-method Class '"rgDataSet"'