Version 0.99.1: Original Version 0.99.2: Bugfix: - Example ERROR fixed, generates ERROR message when no change points are identified. Version 0.99.3: Bugfix: - Example ERROR fixed, generates ERROR message when no change points are identified. Version 0.99.4: Bugfix: - Example ERROR fixed, generates ERROR message when no change points are identified. Version 1.1.0 First Release version Version 1.1.1: New Features: - For more than 3 genes, standard zscore is computed instead of GSVA enrichment scores - For sample size less than 3, zscore can not be computed, program generates an error - SISPA can now run on a single data type or any combination of two numeric data types - changepoint R method options as input parameters - implemented ggplot to create barplot in the freqplot function - Updated vignettes as pdf file to perform 1D and 2D SISPA analysis - SISPA.R numeric ERROR fixed Version 1.1.2: New Features: - cptSamples.R changepoint ERROR fixed Version 1.1.3: New Features: - cptSamples.R Example ERROR fixed - Description File Formatted - Modified Y-axis Label in the function generating the Waterfall Plot - Modified SISPA.R code to input data frame for genes and samples of interest only. - Added change point method option using mean and variance (cpt.meanvar) data - updated SISPA manual Bhakti Dwivedi and Jeanne Kowalski The Winship Cancer Institute, Emory University https://bbisr.winship.emory.edu/