To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("OncoSimulR")

In most cases, you don't need to download the package archive at all.

OncoSimulR

Simulation of cancer progresion with order restrictions

Bioconductor version: 3.0

Functions for simulating and plotting cancer progression data, including drivers and passengers, and allowing for order restrictions. Simulations use continuous-time models (based on Bozic et al., 2010 and McFarland et al., 2013) and fitness functions account for possible restrictions in the order of accumulation of mutations.

Author: Ramon Diaz-Uriarte.

Maintainer: Ramon Diaz-Uriarte <rdiaz02 at gmail.com>

Citation (from within R, enter citation("OncoSimulR")):

Installation

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("OncoSimulR")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("OncoSimulR")

 

PDF R Script OncoSimulR Overview
PDF   Reference Manual
Text   NEWS

Details

biocViews BiologicalQuestion, Software, SomaticMutation
Version 1.0.0
In Bioconductor since BioC 3.0 (R-3.1)
License GPL (>= 3)
Depends R (>= 3.1.0)
Imports Rcpp (>= 0.11.1), parallel, data.table, graph, Rgraphviz
LinkingTo Rcpp
Suggests BiocStyle, knitr, Oncotree
SystemRequirements C++11
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source OncoSimulR_1.0.0.tar.gz
Windows Binary OncoSimulR_1.0.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard)
Mac OS X 10.9 (Mavericks) OncoSimulR_1.0.0.tgz
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