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Combinatorial Polyfunctionality Analysis of Single Cells

Bioconductor version: 2.14

COMPASS is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. COMPASS uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.

Author: Lynn Lin [aut], Kevin Ushey [aut, cre], Greg Finak [aut], Raivo Kolde [ctb] (Author of 'pheatmap', which was modified and now used internally in COMPASS)

Maintainer: Kevin Ushey <kushey at>

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biocViews FlowCytometry, Software
Version 1.2.1
In Bioconductor since BioC 2.14 (R-3.1)
License Artistic-2.0
Depends R (>= 3.0.2)
Imports Rcpp, data.table, RColorBrewer, scales, grid, plyr, knitr, abind, clue, grDevices, utils
Suggests flowWorkspace(>= 3.9.66), shiny, testthat, devtools, Kmisc
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