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Normalization of array CGH data with imbalanced aberrations.

Bioconductor version: 2.13

Normalization and centralization of array comparative genomic hybridization (aCGH) data. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).

Author: Bart P.P. van Houte, Thomas W. Binsl, Hannes Hettling

Maintainer: Bart P.P. van Houte <bvhoute at>

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PDF R Script CGHnormaliter
PDF CGHnormaliter-method.pdf
PDF   Reference Manual


biocViews Microarray, Preprocessing, Software
Version 1.16.0
In Bioconductor since BioC 2.5 (R-2.10)
License GPL (>= 3)
Depends CGHcall(>= 2.17.0), CGHbase(>= 1.15.0)
Imports Biobase, CGHbase, CGHcall, methods, stats, utils
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