fastseg

fastseg - a fast segmentation algorithm

Bioconductor version: 2.10

fastseg implements a very fast and efficient segmentation algorithm. It has similar functionality as DNACopy (Olshen and Venkatraman 2004), but is considerably faster and more flexible. fastseg can segment data from DNA microarrays and data from next generation sequencing for example to detect copy number segments. Further it can segment data from RNA microarrays like tiling arrays to identify transcripts. Most generally, it can segment data given as a matrix or as a vector. Various data formats can be used as input to fastseg like expression set objects for microarrays or GRanges for sequencing data. The segmentation criterion of fastseg is based on a statistical test in a Bayesian framework, namely the cyber t-test (Baldi 2001). The speed-up arises from the facts, that sampling is not necessary in for fastseg and that a dynamic programming approach is used for calculation of the segments' first and higher order moments.

Author: Guenter Klambauer

Maintainer: Guenter Klambauer <fastseg at bioinf.jku.at>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("fastseg")

To cite this package in a publication, start R and enter:

    citation("fastseg")

Documentation

PDF R Script fastseg: Manual for the R package
PDF   Reference Manual

Details

biocViews Classification, CopyNumberVariants, Software
Depends R (>= 2.13), GenomicRanges, Biobase
Imports graphics, stats, IRanges, BiocGenerics
Suggests DNAcopy, oligo,
System Requirements
License LGPL (>= 2.0)
URL http://www.bioinf.jku.at/software/fastseg/fastseg.html
Depends On Me
Imports Me
Suggests Me
Version 1.2.3
Since Bioconductor 2.9 (R-2.14)

Package Downloads

Package Source fastseg_1.2.3.tar.gz
Windows Binary fastseg_1.2.3.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary fastseg_1.2.3.tgz
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