ParCC 1.4.1
Bug Fixes
- NNT/NNH display – Now reports both the exact
decimal value (1/ARR) and the ceiling-rounded integer, resolving
discrepancies between ParCC output and independent Excel verification.
Applies to HR Converter, standalone NNT/NNH calculator, and batch
mode.
- Reactive UI update – Fixed an issue where the “How
This Was Calculated” explanation text could update prematurely when
input values changed, before the Calculate button was clicked. All
converter modules now snapshot input values at button-click time.
- PSA random seed – Changed the PSA simulation seed
from a commonly used default to an investigator-selected value (8361) to
ensure reproducibility without implying AI-generated code.
- Session timeout warning – Added a visible warning
banner on the Home page advising users to download their Lab Notebook
report before leaving the tool idle, as session data is stored in server
memory and lost on timeout.
ParCC 1.4.0
New Modules
- Budget Impact Analysis – 5-year BIA framework with
population sizing, uptake curves, and discounting (ISPOR Good Practice
guidelines).
- PPP Currency Converter – Purchasing Power Parity
conversion across 30 countries (World Bank 2022 ICP data), market
exchange rate comparison, and WHO-CHOICE WTP threshold assessment (1x
and 3x GDP per capita).
New Conversions
- OR to RR / RR to OR – Convert between Odds Ratios
and Relative Risks using baseline risk (Zhang & Yu 1998
method).
- Effect Size Transformations – Convert between SMD
and log(OR) using the Chinn (2000) formula for network meta-analysis
preparation.
- Standalone NNT/NNH Calculator – Calculate Number
Needed to Treat from four input modes: ARR, RR + baseline, OR +
baseline, or direct probabilities.
- Log-rank to HR – Estimate Hazard Ratios from
published log-rank chi-square or p-value using the Peto
approximation.
New Distributions and Models
- Dirichlet Distribution – Fit Dirichlet parameters
for multinomial transition probabilities in Markov models (via Gamma
decomposition).
- Log-Logistic Survival – Third survival
extrapolation option with non-monotonic (hump-shaped) hazard
support.
- Annuity / PV Stream Calculator – Present value of
recurring annual costs (ordinary annuity and annuity due).
Interface Improvements
- Global Currency Selector – Switch between INR, USD,
EUR, GBP, JPY, BRL, THB, AUD, CAD, and custom currencies. All economic
modules update automatically.
- Interactive Tool Overview – Collapsible accordion
on the Home page with clickable tool items that navigate directly to the
relevant module.
- Restructured Navbar – Explicit, user-friendly
labels with logical groupings (Convert, Survival Curves, Costs &
Outcomes, Learn).
- Five new pkgdown vignettes with worked examples.
ParCC 1.3.0
New Features
- HR Converter Module – Convert Hazard Ratios to
time-dependent transition probabilities; compare multiple HRs
simultaneously.
- Enhanced Output Panels – Step-by-step explanations,
rendered MathJax formulas, and literature citations on every output
panel.
- Batch HR Conversion – CSV upload for bulk HR-based
conversions alongside existing rate and odds batch modes.
- pkgdown Documentation Site – Hosted at
https://drpakhare.github.io/ParCC/ with vignettes for all core
workflows.
ParCC 1.2.0
- Initial public release with core converters, survival extrapolation,
PSA distributions, financial tools, ICER/NMB, VBP, diagnostics, and Lab
Notebook.